Abstract Homeobox A5 (HOXA5) is a transcription factor in mammalian and can regulate cell differentiation, proliferation, and apoptosis as well as tumorigenesis.However, little is known on whether and how HOXA5 can regulate the malignant behaviors of cholangiocarcinoma.The methylation levels of HOXA5 were evaluated by methylation microarray and bis
The complex interaction mechanism between state and market economy implies the requirement that public power make use of adequate means and techniques for the difficult role the state has to play within economy.The allocation, distribution and, especially, regulatory role of the state presupposes the promotion of economic policy.The involvement of
This review presents the evidence on the benefits of fixed-dose combination therapy for arterial hypertension management.The focus is on the combination of a third-generation dihydropyridine calcium antagonist lercanidipine and an ACE inhibitor enalapril.Lercanidipine is characterised by high vascular selectivity and 4 pin DIN Cable lipophilicity,
The 2030 Agenda is a clear development milestone for humanity in its ambition to care for our future generations.Smart Cities play an essential role in this development, the development direction of which is based, among others factors, on the fulfilment of the criteria set by the various Sustainable Development Goals (SDGs).The purpose of the curr